When you are under going hormone replacement therapy with our Biote Pellets we recommend a person take the “Core 4” vitamins (nutraceuticals) to enhance their response. We tailor this recommendation to your individual lab results to ensure you are getting what you need, not more, not less. The components of the Core 4 include: DIM, Probiotic, Methyl Factors, and ADK.


DIM (Diindolylmethane)

  • Made from cruciferous vegetables and sulforaphane and pomegranate extract
  • Metabolizes estrogen
  • Decreases the conversion of testosterone to estrogen in men (aromatization)
  • Increases free testosterone
  • Supports weight management
  • Promotes Breast and Prostate health
  • Helps with inflammation
  • 1 capsule a day for women and 2 capsules a day for men
  • Helps your pellets work better and last longer!

ADK (Vitamins A, D3, and K2)

  • 5,000iu or 10,000iu dose available
  • Supports eye health, immune health, promotes healing, decreases acne, maintain bone health, improves energy
  • 1 capsule per day

Methyl Factors

  • Includes methylated B-complex, riboflavin, vitamin B12, and trimethylglycine.
  • Supports healthy estrogen metabolism
  • Energy booster
  • Promotes cardiovascular and neurological health
  • Supports mood
  • 1-3 capsules per day depending on your baseline labs

Probiotic (multistrain probiotic 20B)

  • Promotes digestive/GI health
  • Boosts immune system
  • Helps reduce pain and inflammation
  • Supports hormone balancing
  • Can improve reflux symptoms
  • 1 capsule per day


As always your individualized treatment plan will be based on your lab results and recommendations will be reviewed with you in detail. We offer all these supplements in our clinic as well as several others for other indications. Come check us out!